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An Etiologic Profile of Anemia in 405 Geriatric Patients

机译:405例老年患者贫血的病因

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Background. Anemia is a common condition in the elderly and a significant risk factor for increased morbidity and mortality, reducing not only functional capacity and mobility but also quality of life. Currently, few data are available regarding anemia in hospitalized geriatric patients. Our retrospective study investigated epidemiology and causes of anemia in 405 hospitalized geriatric patients.Methods. Data analysis was performed using laboratory parameters determined during routine hospital admission procedures (hemoglobin, ferritin, transferrin saturation, C-reactive protein, vitamin B12, folic acid, and creatinine) in addition to medical history and demographics.Results. Anemia affected approximately two-thirds of subjects. Of 386 patients with recorded hemoglobin values, 66.3% were anemic according to WHO criteria, mostly (85.1%) in a mild form. Anemia was primarily due to iron deficiency (65%), frequently due to underlying chronic infection (62.1%), or of mixed etiology involving a combination of chronic disease and iron deficiency, with absolute iron deficiency playing a comparatively minor role.Conclusion. Greater awareness of anemia in the elderly is warranted due to its high prevalence and negative effect on outcomes, hospitalization duration, and mortality. Geriatric patients should be routinely screened for anemia and etiological causes of anemia individually assessed to allow timely initiation of appropriate therapy.
机译:背景。贫血是老年人的常见病,并且是增加发病率和死亡率的重要危险因素,不仅会降低功能能力和活动能力,还会降低生活质量。目前,关于住院老年患者贫血的数据很少。我们的回顾性研究调查了405例住院老年患者的流行病学和贫血原因。除了病史和人口统计学资料外,还使用在常规住院治疗过程中确定的实验室参数(血红蛋白,铁蛋白,转铁蛋白饱和度,C反应蛋白,维生素B12,叶酸和肌酐)进行数据分析。贫血影响了大约三分之二的受试者。在386例记录了血红蛋白值的患者中,根据WHO标准,贫血率为66.3%,其中大部分(85.1%)为轻度贫血。贫血主要是由于铁缺乏症(65%),经常由于潜在的慢性感染(62.1%)或混合病因引起的,包括慢性疾病和铁缺乏症,而绝对铁缺乏症起的作用相对较小。老年人对贫血症的认识很高,这是因为它的高患病率以及对结局,住院时间和死亡率的负面影响。应定期筛查老年患者的贫血情况,并单独评估贫血的病因,以便及时开始适当的治疗。

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