The Survival of Nodal Non-Hodgkin’s Lymphoma Patients in the West of Iran

摘要

Background: Most non-Hodgkin’s lymphomas (NHL) arise in lymph nodes or other lymphatic tissues such as the spleen, Waldeyer’s ring and thymus. The aim of study is to evaluate the survival in nodal NHL patients for the first time in the west of Iran. Patients and Methods: Fifty-three patients with nodal NHL referred to Our Clinic from 2002-2014. We checked age, sex, histopathology reports, anatomic sites and survival for them. One representative Material of patients with diffuse large B-cell lymphoma (DLBL), FL, SLL and anaplastic lymphoma was re-classified after revision. The overall survival (OS) was plotted by GraphPad Prism 5 software. Results: For all patients, the median age at diagnosis was 52±16.92 (range, 16-92 years) that 26 patients (49.1%) had age≤50 years. Thirty-four patients (64.2%) were male. Involvement anatomic sites were axillary, neck, inguinal, cervical, mediasten, bone marrow, abdominal, bladder, tonsil and supraclavicular for 11 patients (20.6%), 9(17%), 9(17%), 8(15.2%), 6(11.3%), 5(9.4%), 2(3.8%), 1(1.9%), 1(1.9%) and 1(1.9%), respectively. The 3-year, 5-year and 10-year survival rates are 65%, 54.2% and 51%, respectively. Conclusion: The OS in this study is higher than a number of studies and the median age is lower. Also, the male-to-female ratio for nodal lymphoma is higher than other studies and nodal NHL patients accrue more in males.