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Viscogonioplasty in narrow angle glaucoma: a randomized controlled trial

机译:窄角型青光眼的粘膜角膜成形术:一项随机对照试验

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Purpose: To determine the effect of viscogonioplasty and cataract extraction on intraocular pressure in patients with narrow angle glaucoma.Methods: This was a double-masked randomized controlled trial involving 50 eyes (25 cases and 25 controls) from 38 consecutive patients. All patients underwent phacoemulsification with or without viscogonioplasty. The main outcome measures were intraocular pressure post-treatment and number of glaucoma medications post-treatment.Results: Cases had a greater reduction in intraocular pressure than controls, with a mean intraocular pressure (standard deviation) at 12 months of 13.7 (±2.89) mmHg compared with 16.2 (±3.55) mmHg in controls (P = 0.009). Cases had a greater reduction in mean number of antiglaucoma medications than controls at 12-month review, with 13 of 25 eyes (52%) of cases controlled without any antiglaucoma therapy versus 9 of 25 (36%) of the controls (P = 0.005).Conclusions: Viscogonioplasty combined with cataract extraction has a significantly greater effect than cataract extraction alone on lowering intraocular pressure in patients with poorly controlled narrow angle glaucoma and should therefore be considered as a treatment option for patients with this condition.
机译:目的:确定粘膜成形术和白内障摘除术对窄角型青光眼患者眼内压的影响。方法:这是一项双掩盖随机对照试验,涉及连续38例患者的50眼(25例和25例对照)。所有患者均行超声乳化术,有或无粘膜成形术。主要结局指标为治疗后眼内压和治疗后青光眼药物的使用量。结果:病例的眼内压降低幅度大于对照组,在12个月时的平均眼压(标准差)为13.7(±2.89) mmHg,对照组为16.2(±3.55)mmHg(P = 0.009)。在12个月的检查中,抗青光眼药物的平均减少量比对照组大,在25眼中有13眼(52%)没有进行任何抗青光眼治疗的情况下,与对照组的25眼中有9眼(36%)相比(P = 0.005结论:粘膜成形术联合白内障摘除术对单眼白内障摘除术对窄角型青光眼患者的眼压下降效果明显优于单纯白内障摘除术,因此应被视为这种情况的治疗选择。

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