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Single-molecule DNA detection using a novel SP1 protein nanopore

机译：使用新型SP1蛋白纳米孔进行单分子DNA检测

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摘要

SP1 protein as a new type of biological nanopore is described and is utilized to distinguish single-stranded DNA at the single-molecule level.Using the SP1 nanopore to investigate single molecule detection broadens the existing research areas of pore-forming biomaterials from unsymmetrical biological nanopores to symmetrical biological nanopores.This novel nanopore could provide a good candidate for single-molecule detection and characterization of biomaterial applications.
机译：描述了SP1蛋白作为一种新型的生物纳米孔，并用于在单分子水平上区分单链DNA。使用SP1纳米孔研究单分子检测扩大了非对称生物纳米孔的成孔生物材料的现有研究领域这种新颖的纳米孔可以为生物材料应用的单分子检测和表征提供良好的候选者。

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  • 来源
    《Chemical Communications》 |2013年第17期|1741-1743|共3页
  • 作者

    Hai-Yan Wang; Yang Li; Li-Xia Qin; Arnon Heyman; Oded Shoseyov; Itamar Willner; Yi-Tao Long; He Tian;

  • 作者单位

    Key Laboratory for Advanced Materials and Institute of Fine Chemicals & Department of Chemistry, East China University of Science and Technology Shanghai, P.R.China;

    Key Laboratory for Advanced Materials and Institute of Fine Chemicals & Department of Chemistry, East China University of Science and Technology Shanghai, P.R.China;

    Key Laboratory for Advanced Materials and Institute of Fine Chemicals & Department of Chemistry, East China University of Science and Technology Shanghai, P.R.China;

    The Robert H.Smith Institute of Plant Sciences and Genetics in Agriculture,Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, Israel;

    The Robert H.Smith Institute of Plant Sciences and Genetics in Agriculture,Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, Israel;

    Institute of Chemistry, The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem, Israel;

    Key Laboratory for Advanced Materials and Institute of Fine Chemicals & Department of Chemistry, East China University of Science and Technology Shanghai, P.R.China;

    Key Laboratory for Advanced Materials and Institute of Fine Chemicals & Department of Chemistry, East China University of Science and Technology Shanghai, P.R.China;

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