Detection of a single DNA base-pair mismatch using an anthracene-tagged fluorescent probe

Moran N; Bassani DM; Desvergne JP; Keiper S; Lowden PAS; Vyle JS; Tucker JHR

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Detection of a single DNA base-pair mismatch using an anthracene-tagged fluorescent probe

机译：使用蒽标记的荧光探针检测单个DNA碱基对错配

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摘要

A novel anthracene-tagged oligonucleotide can discriminate between a fully-matched DNA target sequence and one with a single mismatching base-pair through a remarkable difference in fluorescence emission intensity upon duplex formation.

机译：一种新颖的蒽标记寡核苷酸可以通过双链体形成时荧光发射强度的显着差异来区分完全匹配的DNA靶序列和具有单个错配碱基对的寡核苷酸。

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来源
《Chemical Communications》 |2006年第48期|p. 5003-5005|共3页
作者
Moran N; Bassani DM; Desvergne JP; Keiper S; Lowden PAS; Vyle JS; Tucker JHR;
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作者单位

Univ Birmingham, Sch Chem, Birmingham B15 2TT, W Midlands, England;

Univ Bordeaux 1, Chim Organ & Organomet Lab, F-33405 Talence, France;

Queens Univ Belfast, Sch Chem & Chem Engn, Belfast BT9 5AG, Antrim, North Ireland;

Univ London Birkbeck Coll, Sch Biol & Chem Sci, London WC1E 7HX, England;

Univ London Birkbeck Coll, Inst Struct Mol Biol, London WC1E 7HX, England;

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原文格式 PDF
正文语种 eng
中图分类化学;
关键词
BINDING; RNA; OLIGONUCLEOTIDES; POLYMORPHISMS;

机译：结合;RNA;寡核苷酸;多态性;

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1. Single Site Discrimination of Cytosine, 5-Methylcytosine, and 5-Hydroxymethylcytosine in Target DNA Using Anthracene-Tagged Fluorescent Probes [J] . Duprey Jean-Louis H. A., Bullen Gemma A., Zhao Zheng-yun, ACS Chemical Biology . 2016,第3期

机译：使用蒽标记的荧光探针对靶标DNA中的胞嘧啶，5-甲基胞嘧啶和5-羟甲基胞嘧啶进行单点识别
2. Anthracene-modified oligonucleotides as fluorescent DNA mismatch sensors: Discrimination between various base-pair mismatches [J] . Duprey J.-L.H.A., Bassani D.M., Hyde E.I., Supramolecular chemistry . 2011,第3a4期

机译：蒽修饰的寡核苷酸作为荧光DNA错配传感器：区分各种碱基对错配
3. Anthracene-modified oligonucleotides as fluorescent DNA mismatch sensors: discrimination between various base-pair mismatches [J] . Jean-Louis H.A. Duprey, James H.R. Tucker Supramolecular Chemistry . 2011,第3a4期

机译：蒽修饰的寡核苷酸作为荧光DNA错配传感器：区分各种碱基对错配
4. Fluorescent N1-Wyosine Nucleoside: Utility in Mismatch Detection in DNA Duplexes(Abstracts) [C] . Jharna Barman European Symposium on Organic Chemistry . 2007

机译：荧光N1-毛丝核苷：DNA双链体中错配检测的效用（摘要）
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6. DNA mismatch repair in Xenopus egg extracts: repair efficiency and DNA repair synthesis for all single base-pair mismatches. [O] . I Varlet, M Radman, P Brooks 2019

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7. Detection of a single DNA base-pair mismatch using an anthracene-tagged fluorescent probe [O] . Moran N., Bassani D.M., Desvergne J.-P., 2006

机译：使用蒽标记的荧光探针检测单个DNA碱基对错配
8. Subunits of Highly Fluorescent Protein R-phycoerythrin as Probes for Cell Imaging and Single Molecule Detection Doctoral thesis [R] . Isailovic, D. 2005

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Detection of a single DNA base-pair mismatch using an anthracene-tagged fluorescent probe

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