CREG promotes a mature smooth muscle cell phenotype and reduces neointimal formation in balloon-injured rat carotid artery

Yaling Han1* Jie Deng1 Liang Guo1 Chenghui Yan1 Ming Liang1 Jian Kang1 Haiwei Liu1 Alan M. Graham2 and Shaohua Li2

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CREG promotes a mature smooth muscle cell phenotype and reduces neointimal formation in balloon-injured rat carotid artery

机译：CREG促进成熟的平滑肌细胞表型并减少球囊损伤大鼠颈动脉的新内膜形成

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Aim We previously showed that cellular repressor of E1A-stimulated genes (CREG) is up-regulated during serum starvation-induced vascular smooth muscle cell (SMC) differentiation. The aim of this study was to determine the role of CREG in maintaining the quiescent, differentiated phenotype of SMCs both in culture and in balloon-injured rat carotid artery.

机译：目的我们先前显示，在血清饥饿诱导的血管平滑肌细胞（SMC）分化过程中，E1A刺激基因的细胞阻遏物（CREG）被上调。这项研究的目的是确定CREG在维持文化和气球损伤大鼠颈动脉中SMC的静态，分化表型中的作用。

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《Cardiovascular Research》 |2008年第3期|p.597-604|共8页
作者
Yaling Han1* Jie Deng1 Liang Guo1 Chenghui Yan1 Ming Liang1 Jian Kang1 Haiwei Liu1 Alan M. Graham2 and Shaohua Li2;
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1Cardiovascular Research Institute and Department of Cardiology, Shenyang Northern Hospital, 83 Wenhua Road, Shenyang 110016, People's Republic of China 2Department of Surgery, Division of Vascular Surgery, Robert Wood Johnson Medical School-UMDNJ, 125 Paterson Street, New Brunswick, NJ 08903, USA;

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1. CREG promotes a mature smooth muscle cell phenotype and reduces neointimal formation in balloon-injured rat carotid artery. [J] . Han Y, Deng J, Guo L, Cardiovascular Research . 2008,第3期

机译：CREG促进成熟的平滑肌细胞表型并减少球囊损伤大鼠颈动脉的新内膜形成。
2. Histone Demethylase JMJD2A Inhibition Attenuates Neointimal Hyperplasia in the Carotid Arteries of Balloon-Injured Diabetic Rats via Transcriptional Silencing: Inflammatory Gene Expression in Vascular Smooth Muscle Cells [J] . Hu Qi, Zhang Jing, Wu Xiaolin, Cellular Physiology and Biochemistry . 2015,第2期

机译：组蛋白去甲基化酶JMJD2A抑制通过转录沉默减弱气球损伤的糖尿病大鼠颈动脉的内膜增生：血管平滑肌细胞中的炎性基因表达。
3. NK-104, a newly developed HMG-CoA reductase inhibitor, suppresses neointimal thickening by inhibiting smooth muscle cell growth and fibronectin production in balloon-injured rabbit carotid artery. [J] . Kitahara M, Kanaki T, Toyoda K, Japanese Journal of Pharmacology . 1998,第2期

机译：NK-104是一种新开发的HMG-CoA还原酶抑制剂，可通过抑制气球损伤的兔颈动脉中的平滑肌细胞生长和纤连蛋白的产生来抑制新内膜增厚。
4. Phenotype Characterization of Human Coronary Artery Smooth Muscle Cells Using Cyclic Mechanical Strain [C] . Soroor Sharifboor, Craig A Simmons, Rosalind S Labow, Annual meeting of the Society for Biomaterials . 2011

机译：人冠状动脉平滑肌细胞的表型表征使用循环机械应变。
5. The Role of VEGF and Smooth Muscle Phenotype in Hypoxic Remodeling of Ovine Carotid and Cerebral Arteries [D] . Hubbell, Margaret C. 2017

机译：VEGF和平滑肌表型在绵羊颈动脉和脑动脉低氧重塑中的作用
6. Smooth muscle cell‐specific Tgfbr1 deficiency attenuates neointimal hyperplasia but promotes an undesired vascular phenotype for injured arteries [O] . Mingmei Liao, Pu Yang, Fen Wang, 2016

机译：平滑肌细胞特异的Tgfbr1缺乏症减弱新内膜增生但促进血管受损的血管表型
7. CREG promotes a mature smooth muscle cell phenotype and reduces neointimal formation in balloon-injured rat carotid artery [O] . Y. Han, J. Deng, L. Guo, 2008

机译：Creg促进成熟的平滑肌细胞表型，并减少气球损伤大鼠颈动脉的新内膜形成

CREG promotes a mature smooth muscle cell phenotype and reduces neointimal formation in balloon-injured rat carotid artery

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