Genetic alterations between primary head and neck squamous cell carcinoma and recurrence after radiotherapy†

Alberto Deganello MD; Alessandro Franchi MD; Iacopo Sardi MD; Lorenzo Pignataro MD; C. Reneacute; Leemans MD PhD; Oreste Gallo MD

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Genetic alterations between primary head and neck squamous cell carcinoma and recurrence after radiotherapy†

机译：原发性头颈部鳞状细胞癌的遗传改变与放疗后复发†

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AbstractBACKGROUND:In the attempt to characterize the genetic bases of recurrent head and neck squamous cell carcinoma (HNSCC) after radiotherapy (RT), the authors compared the molecular profiles of primary tumors and recurrences.

机译：摘要背景：为了表征放射治疗（RT）后复发性头颈鳞状细胞癌（HNSCC）的遗传基础，作者比较了原发性肿瘤和复发的分子特征。

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来源
《Cancer》 |2010年第5期|p.1291-1297|共7页
作者
Alberto Deganello MD; Alessandro Franchi MD; Iacopo Sardi MD; Lorenzo Pignataro MD; C. Reneacute; Leemans MD PhD; Oreste Gallo MD;
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作者单位

Department of Otolaryngology/Head and Neck Surgery, University of Florence, Florence, Italy;

||Department of Human Pathology and Oncology, University of Florence, Florence, Italy;

|Department of Oncohematology, University of Florence, A. Meyer Children's Hospital, Florence, Italy;

Department of Otolaryngology of the “

Mangiagalli and Regina Elena”

Hospital (IRCCS), University of Milan, Milan, Italy;

Department of Otolaryngology/Head and Neck Surgery, VU University Medical Center, Amsterdam, The Netherlands;

Department of Otolaryngology/Head and Neck Surgery, University of Florence, Florence, Italy;

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正文语种 eng
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关键词
head and neck squamous cell carcinoma; radiotherapy; local recurrence; TP53; microsatellite instability; second field tumor; minimal residual disease;

机译：头颈部鳞状细胞癌;放射治疗;局部复发;TP53;微卫星不稳定性;二次视野肿瘤;最小残留病;

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专利

1. Genetic alterations between primary head and neck squamous cell carcinoma and recurrence after radiotherapy: recurrence, genetically related cancer, or second primary? [J] . Deganello A, Franchi A, Sardi I, Cancer: A Journal of the American Cancer Society . 2010,第5期

机译：原发性头颈部鳞状细胞癌和放疗后复发之间的遗传改变：复发，遗传相关癌或第二原发性？
2. Genetic profile of second primary tumors and recurrences in head and neck squamous cell carcinomas [J] . GutiérrezV.F., MarcosC.á., LlorenteJ.L., Head and neck: Journal for the sciences and specialities of the head and neck . 2012,第6期

机译：头颈部鳞状细胞癌中第二原发肿瘤的遗传特征和复发
3. Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma. [J] . Wang J, Lippman SM, Lee JJ, Carcinogenesis . 2010,第10期

机译：G蛋白信号传导基因调节剂的遗传变异，作为头颈部鳞状细胞癌第二原发肿瘤/复发的易感基因座。
4. Adenylyl Cyclase-Associated Protein 1 in Metastasis of Squamous Cell Carcinoma of the Head and Neck and Non-Small Cell Lung Cancer [C] . G. V. Kakurina, E. S. Kolegova, O. V. Cheremisina, International Conference on Physics of Cancer . 2016

机译：腺苷酸环酶相关蛋白1在头部和颈部和非小细胞肺癌的鳞状细胞癌转移中
5. Epigenetic Regulation of Head and Neck Squamous Cell Carcinoma Chemoresistance, Invasion, and Metastasis. [D] . Chang, Insoon. 2017

机译：头颈部鳞状细胞癌化学耐药性，侵袭和转移的表观遗传学调控。
6. Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma [O] . Jianming Wang, Scott M. Lippman, J.Jack Lee, -1

机译：头颈部鳞状细胞癌继发于第二原发肿瘤/复发的易感基因座——G蛋白信号传导基因调节剂的遗传变异
7. Genetic alterations between primary head and neck squamous cell carcinoma and recurrence after radiotherapy [O] . A.Deganello, A.Franchi, I.Sardi, 2010

机译：原发性头颈部鳞状细胞癌的遗传改变与放疗后复发

Genetic alterations between primary head and neck squamous cell carcinoma and recurrence after radiotherapy†

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