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首页> 外文期刊>Annals of Biomedical Engineering >Flow Visualization of Three-Dimensionality Inside the 12 cc Penn State Pulsatile Pediatric Ventricular Assist Device
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Flow Visualization of Three-Dimensionality Inside the 12 cc Penn State Pulsatile Pediatric Ventricular Assist Device

机译:12 cc Penn州小儿心室辅助装置内部三维流动的可视化

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In order to aid the ongoing concern of limited organ availability for pediatric heart transplants, Penn State has continued development of a pulsatile Pediatric Ventricular Assist Device (PVAD). Initial studies of the PVAD observed an increase in thrombus formation due to differences in flow field physics when compared to adult sized devices, which included a higher degree of three-dimensionality. This unique flow field brings into question the use of 2D planar particle image velocimetry (PIV) as a flow visualization technique, however the small size and high curvature of the PVAD make other tools such as stereoscopic PIV impractical. In order to test the reliability of the 2D results, we perform a pseudo-3D PIV study using planes both parallel and normal to the diaphragm employing a mock circulatory loop containing a viscoelastic fluid that mimics 40% hematocrit blood. We find that while the third component of velocity is extremely helpful to a physical understanding of the flow, particularly of the diastolic jet and the development of a desired rotational pattern, the flow data taken parallel to the diaphragm is sufficient to describe the wall shear rates, a critical aspect to the study of thrombosis and design of such pumps. Keywords Pediatric ventricular assist device - Thrombosis - Fluid dynamics - Particle image velocimetry
机译:为了帮助持续关注小儿心脏移植的器官可用性有限的担忧,宾夕法尼亚州立大学继续开发了一种搏动性小儿心室辅助装置(PVAD)。对PVAD的初步研究发现,与成人尺寸的设备(包括更高的三维度)相比,由于流场物理特性的差异,血栓形成的增加。这种独特的流场使二维平面粒子图像测速(PIV)作为流可视化技术的使用受到质疑,但是PVAD的小尺寸和高曲率使得其他工具(如立体PIV)不可行。为了测试2D结果的可靠性,我们使用平行于和垂直于膜片的平面进行模拟3D PIV研究,采用模拟循环回路,其中包含模拟40%血细胞比容血液的粘弹性流体。我们发现,虽然速度的第三分量对于物理理解流动(特别是舒张射流和形成所需的旋转模式)非常有帮助,但平行于膜片的流动数据足以描述壁的剪切速率,是研究血栓形成和此类泵设计的关键方面。小儿心室辅助装置-血栓形成-流体动力学-粒子图像测速仪

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