Editorial for the Special Issue Squamous Cell Cancer of the Head and Neck—Time to Arrive in the 21st Century of Oncology

摘要

Squamous cell carcinoma of the head and neck (HNSCC) is the sixth most common cancer worldwide. Despite enormous research efforts over the past decades, the prognosis is still rather poor. In non-human papillomavirus (HPV)-related (p16 negative) tumors, the 5-year survival rate is still only 40–60% over all tumor stages. In advanced stages, the 2-year survival is even less, since 30–50% of patients develop local or regional recurrence.