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Development of Floating Tablets of Metformin HCl by Thermoplastic Granulation. Part II: In Vitro Evaluation of the Combined Effect of Acacia Gum/HPMC on Biopharmaceutical Performances

机译：热塑性制粒开发盐酸盐酸二甲双胍浮片。第二部分：相思树胶/ HPMC对生物药物性能的联合作用的体外评估

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摘要

The aim of this study was to evaluate the combined effect, acacia gum(AG)/ hydroxypropylmethylcellulose (HPMC), on biopharmaceutical performances of floating tablets of metformin hydrochloride (MTH) prepared by thermoplastic granulation using stearic acid.

机译：这项研究的目的是评估相思树胶（AG）/羟丙基甲基纤维素（HPMC）对通过硬脂酸热塑造粒制备的盐酸二甲双胍（MTH）浮片的生物药物性能的综合作用。

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期刊名称 Advanced Pharmaceutical Bulletin
作者
Mohamed Djebbar; Nacéra Chaffai; Fatiha Bouchal;
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作者单位

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年(卷),期 2020(10),3
年度 2020
页码 -1
总页数 9
原文格式 PDF
正文语种
中图分类药学;
关键词
Acacia gum; Acacia gum/HPMC Combination; Floating tablets; Metformin HCl; Stearic acid; Thermoplastic granulation;

机译：相思树胶;相思树胶/ HPMC组合;漂浮片剂;盐酸二甲双胍;硬脂酸;热塑性制粒;

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专利

1. Design, optimization and in vitro - in vivo evaluation of bilayer floating tablets of diltiazemHCl by using xanthan gum and guar gum in healthy human volunteers [J] . D. V. R. N. Bhikshapathi, J. Prasanna Kumari, K. N. Jayaveera, Der Pharmacia Lettre . 2013,第5期

机译：黄原胶和瓜尔胶在健康人体志愿者中设计，优化和盐酸地尔硫卓双层漂浮片的体外-体内评价
2. Design and In-vitro Evaluation of Sustained Release Floating Tablets of Metformin HCl Based on Effervescence and Swelling [J] . Jaffri Juliana Md., Mahmood Syed, Mandal Uttam, Iranian Journal of Pharmaceutical Research . 2016,第1期

机译：基于泡腾和溶胀的盐酸二甲双胍缓释漂浮片的设计及体外评价
3. FORMULATION AND EVALUATION OF SUSTAINED RELEASE FLOATING TABLETS OF PIOGLITAZONE EMPLOYING OLIBANUM GUM AND HPMC [J] . CHINNA DEVI GAJULA, BHASKARA RAO RAYANI Asian Journal of Pharmaceutical and Clinical Research . 2012,第1期

机译：使用奥利巴姆胶和HPMC的吡格列酮缓释漂浮片的配方与评价
4. Development of an extended release metformin HCl-hydroxypropyl cellulose and -hypromellosematrix tablets and effect of additives on the drug release kinetics [C] . N.K.Patel, N.P.Desai, M.A.Patel Annual meeting exposition of the Controlled Release Society . 2009

机译：盐酸二甲双胍-羟丙基纤维素和-羟丙甲纤维素片的缓释和添加剂对药物释放动力学的影响
5. Development of an extended release metformin HCl-hydroxypropyl methylcellulose/hydroxypropyl cellulose matrix tablets and effect of additives on the drug release mechanism. [D] . Patel, Mehulkumar A. 2010

机译：盐酸二甲双胍盐酸盐-羟丙基甲基纤维素/羟丙基纤维素基质片剂的开发以及添加剂对药物释放机理的影响。
6. Design and In-vitro Evaluation of Sustained Release Floating Tablets of Metformin HCl Based on Effervescence and Swelling [O] . Faria Gias Senjoti, Syed Mahmood, Juliana Md Jaffri, 2016

机译：基于泡腾和溶胀的盐酸二甲双胍缓释浮片的设计及体外评价
7. FORMULATION DESIGN AND OPTIMIZATION OF ORAL FLOATING MATRIX TABLETS OF CIPROFLOXACIN HCL BY USING HPMC AND XANTHAN GUM WITH EXPERIMENTAL DESIGN [O] . Gourishyam Pasa, Prasanta Kumar Choudhury, Ghanshyam Panigrahi 2018

机译：用HPMC和黄原胶与实验设计，使用HPMC和黄原胶气浮动基质片剂的配方设计与优化

Development of Floating Tablets of Metformin HCl by Thermoplastic Granulation. Part II: In Vitro Evaluation of the Combined Effect of Acacia Gum/HPMC on Biopharmaceutical Performances

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