Comparative analysis of dose-dependent neurotoxic response to 1-methyl-4-phenyl-1236-tetrahydropyridine in C57BL/6 N mice derived from three different sources

摘要

Comparative analysis of physiological responses to acute MPTP administration (four injections at two-hour intervals) among different stocks of C57BL/6 mice. - Dose-dependent changes in body weight and ( - ) temperature (hypothermic response) over an eight hour period. Distribution and dose-dependent changes in mouse body composition (total mass, lean mass, and fat tissue). Values are presented as mean ± SD; each group consisted of 6–15 mice. *  p p