Sweets Syndrome as Manifestation of Active Ulcerative Colitis

摘要

A 63-year-old woman with an extensive ulcerative colitis (UC) diagnosed over a decade ago presented with a history of abrupt onset of fever and erythematous nodular skin lesions, as well as increased bloody diarrhea and osteoarticular pain. She had been treated with mesalazine, azathioprine (suspended due to side effects), and infliximab (IFX). Physical examination showed the presence of erythematous skin lesions (Fig. , , ). Blood analysis revealed elevated inflammatory markers, low circulating IFX levels, and significantly high anti-IFX antibodies. We performed a colonoscopy which evidenced signs compatible with active severe UC (Mayo endoscopic subscore: 3). Consequently, the patient was started on systemic corticotherapy.