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The Genome of Setaria digitata: A Cattle Nematode Closely Related to Human Filarial Parasites

机译:狗尾草的基因组:与人类丝虫寄生虫密切相关的牛线虫

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摘要

Here we present the draft genome sequence of , a parasitic nematode affecting cattle. Due to its similarity to , the parasitic nematode that causes lymphatic filariasis in humans, has been used as a model organism at the genomic level to find drug targets which can be used for the development of novel drugs and/or vaccines for human filariasis. causes cerebrospinal nematodiasis in goats, sheep, and horses posing a serious threat to livestock in developing countries. The genome sequence of will assist in finding candidate genes to use as drug targets in both and . The assembled draft genome is ∼90 Mb long and contains 8,974 genomic scaffolds with a G+C content of 31.73%.
机译:在这里,我们介绍了影响牛的寄生线虫的基因组序列草案。由于其与引起人类淋巴丝虫病的寄生线虫相似,已在基因组水平上用作模型生物,以寻找可用于开发新型药物和/或人丝虫病疫苗的药物靶标。引起山羊,绵羊和马的脑脊髓线虫病对发展中国家的牲畜构成严重威胁。的基因组序列将帮助寻找候选基因用作两者的药物靶标。组装的草图基因组长约90 Mb,包含8,974个基因组支架,G + C含量为31.73%。

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