Adherence in the treatment of patients with extensively drug-resistant tuberculosis and HIV in South Africa: A prospective cohort study

摘要

ObjectiveExtensively drug-resistant tuberculosis (XDR-TB)/HIV co-infection is difficult to treat with frequent adverse drug reactions, and high mortality. Adherence to antiretroviral therapy (ARV) and second-line TB medications may reduce mortality, prevent amplification of drug-resistance, and improve outcomes.