Hyaluronan thiomer gel/matrix mediated healing of articular cartilage defects in New Zealand White rabbits—a pilot study

机译：透明质酸硫醇聚合物凝胶/基质介导的新西兰白兔关节软骨缺损的愈合—一项初步研究

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摘要

BackgroundArticular cartilage defects are limited to their regenerative potential in human adults. Our current study evaluates tissue regeneration in a surgically induced empty defect site with hyaluronan thiomer as a provisional scaffold in a gel/matrix combination without cells on rabbit models to restore tissue formation.

机译：背景技术关节软骨缺损限于其在成人中的再生潜力。我们当前的研究评估了透明质酸巯基聚合物作为凝胶/基质组合中的临时支架，以手术诱导的空缺位部位的组织再生，在兔模型上没有细胞可恢复组织形成。

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期刊名称 Journal of Experimental Orthopaedics
作者
Christoph Bauer; Vivek Jeyakumar; Eugenia Niculescu-Morzsa; Daniela Kern; Stefan Nehrer;
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作者单位

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年(卷),期 2017(4),-1
年度 2017
页码 14
总页数 8
原文格式 PDF
正文语种
中图分类外科学;
关键词
Animal models Chondrocytes Articular cartilage Polymers Biomaterials;

机译：动物模型;软骨细胞;关节软骨;聚合物;生物材料;

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专利

1. Hyaluronan thiomer gel/matrix mediated healing of articular cartilage defects in New Zealand White rabbits—a pilot study [J] . Christoph Bauer, Vivek Jeyakumar, Eugenia Niculescu-Morzsa, Journal of experimental orthopaedics. . 2017,第1期

机译：透明质酸硫醇聚合物凝胶/基质介导的新西兰白兔关节软骨缺损的愈合—一项初步研究
2. Regeneration of articular cartilage defects in the temporomandibular joint of rabbits by fibroblast growth factor-2: a pilot study. [J] . Takafuji H, Suzuki T, Okubo Y, International journal of oral and maxillofacial surgery . 2007,第10期

机译：通过成纤维细胞生长因子2再生家兔颞下颌关节软骨缺损的初步研究。
3. Comparative Effectiveness of Bone Grafting Using Xenograft Freeze-Dried Cortical Bovine, Allograft Freeze-Dried Cortical New Zealand White Rabbit, Xenograft Hydroxyapatite Bovine, and Xenograft Demineralized Bone Matrix Bovine in Bone Defect of Femoral Diaphysis of White Rabbit: Experimental Study In Vivo [J] . Ferdiansyah Mahyudin, Dwikora Novembri Utomo, Heri Suroto, International Journal of Biomaterials . 2017,第期

机译：骨移植的比较效果使用异种移植冻干皮质牛，同种异体移植冻干皮质新西兰白兔，异种移植羟基磷灰石牛，异种移植脱矿质骨基质牛骨缺陷白兔骨缺损：实验研究体内实验研究
4. Repair of Full-thickness Defects in Rabbit Articular Cartilage Using bFGF and Hyaluronan Sponge [C] . T. Yamazaki, J. Tarpu.ra, T, International Symposium on Ceramics in Medicine . 2004

机译：使用BFGF和Hyaluronan海绵修复兔关节软骨的全厚缺陷
5. Adrenocortical dysfunction induced by cholesterol feeding in New Zealand white rabbits: Correlated morphometric and biochemical study. [D] . Apkarian, Robert Phillip. 1997

机译：胆固醇喂养新西兰白兔诱发的肾上腺皮质功能障碍：相关的形态学和生化研究。
6. Comparative Effectiveness of Bone Grafting Using Xenograft Freeze-Dried Cortical Bovine Allograft Freeze-Dried Cortical New Zealand White Rabbit Xenograft Hydroxyapatite Bovine and Xenograft Demineralized Bone Matrix Bovine in Bone Defect of Femoral Diaphysis of White Rabbit: Experimental Study In Vivo [O] . Ferdiansyah Mahyudin, Dwikora Novembri Utomo, Heri Suroto, 2017

机译：异种移植冷冻干燥皮质牛异种移植冷冻干燥皮质新西兰白兔异种移植羟基磷灰石牛和异种脱钙骨基质牛在白兔股骨干骨缺损中移植骨的比较有效性：体内实验研究
7. 393 CANCELLOUS BONE MATRIX GELATIN CONTAINING ALLOGENIC CHONDROCYTES FOR THE REPAIR OF FULL-THICKNESS ARTICULAR CARTILAGE DEFECTS: RESULTS OF A 1 YEAR STUDY IN RABBITS [O] . Cao J., Yang B., Zhang A., 2007

机译：393含同种异体软骨细胞的松质骨基质明胶修复全层软骨软骨缺损：一项为期一年的兔子研究结果

Hyaluronan thiomer gel/matrix mediated healing of articular cartilage defects in New Zealand White rabbits—a pilot study

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