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Time course and prognostic value of serum GFAP pNFH and S100β concentrations in dogs with complete spinal cord injury because of intervertebral disc extrusion

机译：椎间盘突出导致完全性脊髓损伤的犬的血清GFAPpNFH和S100β浓度的时程和预后价值

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摘要

BackgroundA noninvasive biomarker is needed to predict recovery from severe spinal cord injury (SCI) because of thoracolumbar intervertebral disc extrusion (TL‐IVDE). Proteins released from neural and glial cells can be detected in the blood and show promise as prognostic tools, but their concentration is influenced by time after injury.

机译：背景技术由于胸腰椎椎间盘突出症（TL‐IVDE），需要一种非侵入性生物标志物来预测严重脊髓损伤（SCI）的恢复。从神经细胞和神经胶质细胞释放的蛋白质可以在血液中检测到，并有望作为一种预后工具，但其浓度受损伤后时间的影响。

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期刊名称 Journal of Veterinary Internal Medicine
作者
Natasha J. Olby; Ji‐Hey Lim; Nikki Wagner; Natalia Zidan; Peter J. Early; Christopher L. Mariani; Karen R. Muñana; Eric Laber;
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作者单位

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年(卷),期 2019(33),2
年度 2019
页码 726–734
总页数 9
原文格式 PDF
正文语种
中图分类动物医学（兽医学）;
关键词
biomarker intervertebral disc disease myelomalacia prognosis;

机译：生物标志物;椎间盘疾病;脊髓软化症;预后;

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1. Time course and prognostic value of serum GFAP, pNFH, and S100β concentrations in dogs with complete spinal cord injury because of intervertebral disc extrusion [J] . Natasha J. Olby, Ji‐Hey Lim, Nikki Wagner, Journal of Veterinary Internal Medicine . 2019,第2期

机译：椎间盘突出导致完全性脊髓损伤的狗的血清GFAP，pNFH和S100β浓度的时程和预后价值
2. A simplified method of walking track analysis to assess short-term locomotor recovery after acute spinal cord injury caused by thoracolumbar intervertebral disc extrusion in dogs [J] . Song R. B., Oldach M. S., Basso D. M., The Veterinary Journal . 2016,第Null期

机译：评估犬胸腰椎椎间盘突出引起的急性脊髓损伤后短期运动恢复的步行轨迹分析的简化方法
3. von Frey anesthesiometry to assess sensory impairment after acute spinal cord injury caused by thoracolumbar intervertebral disc extrusion in dogs [J] . Song R. B., Basso D. M., Da Costa R. C., The Veterinary Journal . 2016,第Null期

机译：von Frey麻醉仪评估狗胸腰椎椎间盘突出引起的急性脊髓损伤后的感觉障碍
4. DO DOGS SPINAL WALK? ELECTROPHYSIOLOGIC CHARACTERIZATION OF LONG TRACT INTEGRITY IN CANINE SPINAL CORD INJURY [C] . Melissa Lewis, Natasha Olby Conference of the American^College^of^Veterinary^Internal^Medicine . 2016

机译：狗脊柱散步吗？犬脊髓损伤中长道完整性的电生理特征
5. Review of the pathogenesis and treatment of acute spinal cord injury and investigation into the use of urine 3-HPMA as a novel biomarker of secondary injury after acute spinal cord injury in the dog. [D] . Sangster, Andrea. 2014

机译：回顾急性脊髓损伤的发病机理和治疗方法，并探讨使用尿液3-HPMA作为犬急性脊髓损伤后继发性损伤的新型生物标志物。
6. von Frey anesthesiometry to assess sensory impairment after acute spinal cord injury caused by thoracolumbar intervertebral disc extrusion in dogs [O] . R.B. Song, D.M. Basso, R.C. da Costa, -1

机译：von Frey麻醉仪评估犬胸腰椎椎间盘突出引起的急性脊髓损伤后的感觉障碍
7. Consequences of intraoperative spinal cord manipulation in dogs with thoracolumbar intervertebral disc extrusion [O] . C.C. Diogo, E.A. Tudury, M.A. Bonelli, 2017

机译：胸腰椎间盘突出症犬术中脊髓手术的后果
8. Prognostic Significance of Concentrations of Four Classes of Protein-Bound Carbohydrates in the Serum of Dogs. [R] . evans, a. s. quinn, f. a. 1971

机译：四种蛋白结合碳水化合物浓度在犬血清中的预后意义。

Time course and prognostic value of serum GFAP pNFH and S100β concentrations in dogs with complete spinal cord injury because of intervertebral disc extrusion

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