Using agar and broth dilutions, Sch 34343 was found to be highly active against gram-positive and gram-negative aerobic, facultatively anaerobic, and anaerobic bacteria, with the exceptions of enterococci, methicillin-resistant staphylococci, and Pseudomonas spp., which were resistant. Comparisons were made with imipenem, cefuroxime, cefotaxime, gentamicin, clindamycin, and metronidazole.
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