Genistein-triggered anticancer activity against liver cancer cell line HepG2 involves ROS generation mitochondrial apoptosis G2/M cell cycle arrest and inhibition of cell migration

摘要

IntroductionLiver cancer is one of the most common malignancies across the globe and one of the major causes of cancer-related mortality. With limited available treatment options, there is an urgent need to look for new available options. Genistein is an important plant flavonoid and has been shown to possess tremendous pharmacological potential. The objective of the present study was therefore to evaluate the anticancer effect of the genistein.