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Parallel-META: efficient metagenomic data analysis based on high-performance computation

机译:Parallel-META:基于高性能计算的高效宏基因组数据分析

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摘要

BackgroundMetagenomics method directly sequences and analyses genome information from microbial communities. There are usually more than hundreds of genomes from different microbial species in the same community, and the main computational tasks for metagenomic data analyses include taxonomical and functional component examination of all genomes in the microbial community. Metagenomic data analysis is both data- and computation- intensive, which requires extensive computational power. Most of the current metagenomic data analysis softwares were designed to be used on a single computer or single computer clusters, which could not match with the fast increasing number of large metagenomic projects' computational requirements. Therefore, advanced computational methods and pipelines have to be developed to cope with such need for efficient analyses.
机译:背景技术基因组学方法直接对微生物群落的基因组信息进行测序和分析。同一社区中通常有来自不同微生物物种的数百个基因组,宏基因组学数据分析的主要计算任务包括微生物群落中所有基因组的分类和功能成分检查。元基因组数据分析需要大量的数据和计算,这需要大量的计算能力。当前大多数宏基因组学数据分析软件被设计用于单台计算机或单个计算机集群,这与大型宏基因组学项目对计算需求的快速增长无法匹配。因此,必须开发先进的计算方法和管线以应对对有效分析的这种需求。

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