13C glucose labelling studies using 2D NMR are a useful tool for determining ex vivo whole organ metabolism during hypothermic machine perfusion of kidneys

摘要

BackgroundThe aim of this study is to determine the feasibility of using nuclear magnetic resonance (NMR) tracer studies (¹³C-enriched glucose) to detect ex vivo de novo metabolism in the perfusion fluid and cortical tissue of porcine kidneys during hypothermic machine perfusion (HMP).