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ABCB1 C3435T polymorphism and the lipid-lowering response in hypercholesterolemic patients on statins: a meta-analysis

机译：ABCB1 C3435T基因多态性和高胆固醇血症患者对他汀类药物的降脂反应：一项荟萃分析

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BackgroundA number of researches have evaluated the association between the ABCB1 polymorphism and the lipid-lowering response of statins, but the results have been inconclusive. To examine the lipid-lowering efficacy and safety associated with the ABCB1 C3435T polymorphism in hypercholesterolemic patients receiving statin, all available studies were included in this meta-analysis.

机译：背景许多研究评估了ABCB1多态性与他汀类药物的降脂反应之间的关系，但结果尚无定论。为了检查与接受他汀类药物的高胆固醇血症患者的ABCB1 C3435T多态性相关的降脂功效和安全性，所有荟萃分析均纳入了所有可用研究。

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期刊名称 Lipids in Health and Disease
作者
Jia Su; Hongyu Xu; Jun Yang; Qinglin Yu; Shujun Yang; Jianjiang Zhang; Qi Yao; Yunyun Zhu; Yuan Luo; Lindan Ji; Yibo Zheng; Jingbo Yu;
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作者单位

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年(卷),期 2015(14),-1
年度 2015
页码 122
总页数 10
原文格式 PDF
正文语种
中图分类分子生物学;
关键词
ABCB1 Polymorphism Statin Serum lipid level Myopathy Meta-analysis;

机译：ABCB1;多态性;他汀类药物;血脂水平;肌病;荟萃分析;

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专利

1. ABCB1 C3435T polymorphism and the lipid-lowering response in hypercholesterolemic patients on statins: a meta-analysis [J] . Jia Su, Hongyu Xu, Jun Yang, Lipids in Health Disease . 2015,第3期

机译：ABCB1 C3435T基因多态性和高胆固醇血症患者对他汀类药物的降脂反应：一项荟萃分析
2. Concurrent effects of ABCB1 C3435T, ABCG2 C421A, and XRCC1 Arg194Trp genetic polymorphisms with risk of cancer, clinical output, and response to treatment with imatinib mesylate in patients with chronic myeloid leukemia [J] . Salimizand Hana, Amini Sabrieh, Abdi Mohammad, Tumour biology : . 2016,第1期

机译：慢性粒细胞白血病患者中ABCB1 C3435T，ABCG2 C421A和XRCC1 Arg194Trp基因多态性与癌症风险，临床输出和甲磺酸伊马替尼治疗反应的并发影响
3. Genetic polymorphisms of CYP2C19*2 and ABCB1 C3435T affect the pharmacokinetic and pharmacodynamic responses to clopidogrel in 401 patients with acute coronary syndrome [J] . Wang Xia-qin, Shen Chen-lin, Wang Bang-ning, Gene: An International Journal Focusing on Gene Cloning and Gene Structure and Function . 2015,第2期

机译：CYP2C19 * 2和ABCB1 C3435T的遗传多态性影响401例急性冠脉综合征患者对氯吡格雷的药代动力学和药效学反应
4. Statins and Lipid-Lowering Strategies in Cardiorenal Patients [C] . Stefano Bianchi, Daniela Grimaldi, Roberto Bigazzi Annual International Vicenza Course on Hemodialysis . 2011

机译：体外患者中的他汀类药物和降脂策略
5. Pharmacogenetic analysis of dopamine and glutamate receptor gene polymorphisms and clinical response to clozapine in patients with schizophrenia [D] . Hwang, Rudi 2014

机译：精神分裂症患者多巴胺和谷氨酸受体基因多态性的药理学分析和对氯氮平的临床反应
6. ABCB1 C3435T Polymorphism and Response to Clopidogrel Treatment in Coronary Artery Disease (CAD) Patients: A Meta-Analysis [O] . Jia Su, Jin Xu, Xiaojing Li, -1

机译：aBCB1 C3435T多态性与响应氯吡格雷治疗冠状动脉疾病（CaD）患者的meta分析
7. C3435T polymorphism and the lipid-lowering response in hypercholesterolemic patients on statins: a meta-analysis [O] . 2015

机译：高胆固醇血症患者对他汀类药物的C3435T基因多态性和降脂反应：一项荟萃分析

ABCB1 C3435T polymorphism and the lipid-lowering response in hypercholesterolemic patients on statins: a meta-analysis

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