The Predictive and Prognostic Significance of c-erb-B2 EGFR PTEN mTOR PI3K p27 and ERCC1 Expression in Hepatocellular Carcinoma

摘要

BackgroundHepatocellular carcinoma (HCC) is the fifth most common fatal cancer and an important healthcare problem worldwide. There are many studies describing the prognostic and predictive effects of epidermal growth factor receptor 2 (c-erb-B2) and epidermal growth factor receptor 1 (EGFR), transmembrane tyrosine kinases that influence cell growth and proliferation in many tumors.