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Breast milk pasteurisation in developed countries to reduce HIV transmission. Do the benefits outweigh the risks?

机译:发达国家进行母乳巴氏消毒以减少艾滋病毒的传播。收益大于风险吗?

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摘要

BACKGROUND: Transmission of HIV through breastfeeding is well documented. The World Health Organisation advise HIV-infected women in developed countries to use alternatives to breastfeeding together with highly active antiretroviral therapy and optimal management of delivery to prevent transmission of HIV to their infant. CASE REPORT: We present the case of an HIV-infected woman electing to exclusively breastfeed for six months and applying milk pasteurisation techniques without transmission to her infant. Two paired samples of her breast milk were tested for HIV RNA prior to and after pasteurisation. The first pair of specimens reported no change in HIV RNA copy number, the second pair of specimens reported an increase in copy number. DISCUSSION: This technique, the evidence for HIV inactivation and the effects pasteurisation has on nutritional and immunological components of breast milk are discussed. CONCLUSION: In conclusion, we believe there is currently insufficient data to recommend this technique either as a safe alternative to formula feeding in resource-rich countries or as a method for providing intact immunological components of breast milk to the infant.
机译:背景:有充分的证据证明通过母乳喂养传播艾滋病毒。世界卫生组织建议发达国家的受艾滋病毒感染的妇女使用母乳喂养以外的替代方法,同时使用高效的抗逆转录病毒疗法和最佳的分娩管理方法,以防止艾滋病毒传染给婴儿。病例报告:我们介绍了一名艾滋病毒感染妇女选择完全母乳喂养六个月并应用牛奶巴氏杀菌技术而不会传染给婴儿的案例。在巴氏灭菌之前和之后,对两对母乳样品进行了HIV RNA检测。第一对样本报告HIV RNA拷贝数没有变化,第二对样本报告拷贝数增加。讨论:讨论了这项技术,HIV灭活的证据以及巴氏灭菌对母乳的营养和免疫成分的影响。结论:总的来说,我们认为目前尚无足够的数据推荐该技术,作为在资源丰富的国家中代替配方奶喂养的安全替代方法,或作为向婴儿提供完整的母乳免疫成分的方法。

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