cqvip:Background and Study Aim: Ensdoscopic ultrasound- gui- ded fine- needle aspiration (EUS- FNA) has been reported as a useful techni que for histological diagnosis of submucosal or extrinsic gastrointestinal and p ancreatic lesions. The aim of this study was to evaluate the use of EUS- FNA fo r the diagnosis of lesions either within or adjacent to the wall of the colon an d rectum. Patients and Methods: A total of 22 patients with a lesion within the wall of, or adjacent to, the colon or rectum underwent EUS- FNA. They were divi ded into two groups: patients who had previously had a malignancy (the “ previo us + ve" group, n=11), and patients who had not previously had a malignancy (th e “ previous - ve" group, n = 11). In the four patients who had lesions locate d proximal to the sigmoid colon, EUS- FNA was performed using a guide wire and overtube. The success rates for adequate tissue sampling and for detecting malig nant and benign masses by EUS- FNA were evaluated and the success rate for dete ction was compared with the success rate of EUS and computed tomography. Results : Sufficient tissue for evaluation was obtained from 21 of be 22 patients (95.5 % ). The overall rate of detection of malignant and benign masses was 95.5% ( 21/22) for EUS- FNA and 81.8% (18/22) for pre- EUS- FNA imaging investigati ons. Of the 11 patients in the previous + ve group, ten were diagnosed with recurrences of primary malignancies; of the 11 patients in the previous - ve group, four we re diagnosed with primary malignancies and seven were diagnosed with benign lesi ons. There were no complications related to the EUS- FNA procedure. Conclusions : EUS- FNA is a safe techniquewhich is useful in the planning of treatment for patients who have a mass within the wall or adjacent to the wall of the entire l ength of the colon or rectum.
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