中医药对高血压前期血压影响的 Meta 分析

摘要

目的：系统评价中医药对高血压前期血压的影响。方法：计算机检索国内外关于中医药干预高血压前期的临床随机对照试验，使用I2评估各研究之间的异质性，并用RevMan 5.2.0软件进行Meta分析。结果：共纳入8篇文献，1005例受试者。 Meta分析结果提示，与对照组相比，试验组在降低收缩压（ WMD：－3.65；95％CI：－5.35～－1.94；I2∶87％）及舒张压（ WMD：－2.58；95％CI：－4.30～－0.86；I2∶93％）方面均优于对照组，2组间的差异具有统计学意义（ P＜0.01）。结论：在生活方式干预的基础上，加用中医药干预有助于进一步降低血压水平。%Objective:To evaluate the effect of Chinese herbal medicine on blood pressure in pre-hypertensive cases .Methods:Domestic and international databases were searched for relevant randomized controlled trials (RCTs)which investigated the effect of Chinese herbal medicine on blood pressure in pre-hypertensive cases .Heterogeneity of cross-studies was assessed ,using I2.All me-ta-analyses were conducted through RevMan 5.2.0.Results:Eight RCTs involving 1005 subjects were selected .Meta-analysis dem-onstrated that the test group reduces the level of both systolic blood pressure (WMD:-3.65;95%CI:-5.35~-1.94;P<0.01, I2:87%) and diastolic blood pressure ( WMD:-2.58;95%CI:-4.30~-0.86;P<0.01;I2:93%) ,compared with the control group.The difference was statistically significant .Conclusion:Basing on lifestyle intervention ,Chinese herbal medicine helped re-ducing the level of blood pressure .