三地益血汤联合西药治疗ITP36例临床观察

摘要

目的:观察三地益血汤联合西药治疗特发性血小板减少性紫癜(ITP)的临床疗效.方法:选择70例ITP 患者,随机分为对照组和治疗组.2 组均以胸腺肽80 mg+5% 葡萄糖(GS) 250 mL 静脉滴注,1次/d;参麦注射液50 mL+5% GS 250 mL静脉滴注,1次/d;泼尼松,1 mg/(kg·d),口服;氨肽素,5粒/次,3次/d;血小板＜30×109/L者给予环孢素A,30 mg/ 次,口服.治疗组在常规治疗的基础上给予自拟三地益血汤.2 组均以治疗14天为1 个疗程,治疗2 个疗程后观察疗效.结果:总有效率治疗组为94.44%,对照组为85.29%,2 组相比差异有统计学意义(P＜0.05).2 组均未见明显不良反应.结论:三地益血汤联合西药治疗ITP 提高临床疗效,减少西药副作用.%Objective: To observe clinical effects of SanDi YiXueTang and western medicine in treating idiopathic thrombocytopenic purpura (ITP). Method: All 70 patients with ITP were randomized into control group and treatment group. Both groups received 80mg of thymic peptide and 250mL of 5% glucose through intravenous drip, once per day; 50 mL of ShenMai injection and 250 mL of 5% glucose through intravenous drip, once per day; prednisone, 1 mg/ (kg · d), oral; ampeptide elemente, five pills once, three times per day; ciclosporin A was given to the patient whose blood platelets were less than 30×109/L, 30 mg per day, oral. Treatment group took self-design SanDi YiXueTang. For both groups one session was 14 days and curative effects were observed after two sessions. Result: Total effective rate of treatment group was 94.44%, higher than 85.29% of control group with statistical meaning(P<0.05). No adverse reaction occurred in both groups. Conclusion: SanDi YiXueTang combined with western medicine can improve clinical effects and reduce side effects of western medicine.