生物可降解冠状动脉支架的研究进展

摘要

In today's aging society,coronary heart disease has become one of the most important killers of human health. As the most important instrument in cardiovascular intervention,the efficacy of endovascular stents determines the success of intervention. It has undergone three eras:the bare metal stent,drug-eluting stent,and biodegradable stent. By summarizing clinical trials of biodegradable scaffolds,this paper illustrates the development of this type of stent in general,pointing out the current difficulties we are faced with and the future direction for research.%在如今的老龄化社会中，冠心病已成为人类健康的一大杀手，血管支架作为心血管介入治疗的最主要的器械，其效能决定了介入手术的成败。冠状动脉冠脉支架的发展先后经历了裸金属支架、药物洗脱支架和生物可降解支架3个时代。该文通过归纳目前使用的生物可降解支架的临床试验，来阐述可降解冠脉支架大体的发展历程，指出目前疗效及所面临的难题，并对支架发展的未来作一展望。