双引导下阿霉素介入治疗三叉神经痛的回顾性分析

摘要

目的 观察X线机引导下神经刺激器发出不同刺激电流强度下阿霉素半月神经节介入治疗三叉神经痛近期与远期疗效的不同.方法 103例原发性三叉神经痛患者在C型臂X光机引导下根据神经刺激器发出的不同刺激电流分为3组:A组刺激电流＜0.1 mA,B组刺激电流0.1～0.4 mA,C组刺激电流＞0.4 mA.用McGill评分疼痛分级指数( PRI)总分、现有疼痛强度(PPI)、VAS、疼痛缓解有效率和介入治疗副作用随访记录3组患者术后1、2、4、8、16、24个月的不同.结果 A组与C组PRI总分、VAS在术后16、24个月有差异(P＜0.05),PPI评分在术后24个月有差异(P＜0.05)；B组与C组PRI在术后24个月有差异(P＜0.05).结论 阿霉素半月神经节介入治疗三叉神经痛,神经刺激器发出的电流强度越小,神经毁损的近期与远期疗效越好.%Objective To investigate the differences of the short-term and long-term therapeutic efficacy of adriamy cin injection around trigeminal ganglion for treatment of trigeminal neuralgia under the guidance of X-ray and different elec tric stimulation generated by neurostimulator. Methods A total of 103 patients with trigeminal neuralgia were divided into three groups on the basis of different electric stimulation; Group A (the stimulated current was lower than 0. 1 mA) , Group B (the stimulated current was between 0. 1 mA and 0. 4 mA) , Group C (the stimulated current was higher than 0. 4 mA). Total score of PRI, PPI, VAS of McGill and the rate of effectiveness and adverse effects were recorded at 1,2, 4, 8, 16, 24 months after treatment. Results There were significant differences of PRI, VAS between Group A ( n - 35 ) and Group C (re = 30) at 16, 24 months (P < 0. 05) , the difference of PPI between Group A and Group C was significant at 24 months (P<0.05) , the difference of PRI between Group B (n =38) and Group C was significant at 24 months (P < 0.05). Conclusion The lower the electric stimulation generated by neurostimulator, the better the short-term and long term therapeutic efficacy of adriamycin injection around trigeminal ganglion for treatment of trigeminal neuralgia.