本文主要对光果甘草中光甘草定、甘草酸两种重要活性成分的同时提取工艺进行了研究.通过单因素试验确定了影响提取的主要因素及适宜水平范围,通过正交试验确定了其最佳提取条件为:用含0.6%氨水的60%乙醇溶液作为提取剂,料液比为1:20(w:v),在75℃条件下提取2 h.最佳提取条件下光甘草定的得率为0.238%±0.002%,甘草酸的得率为5.08%±0.03%.该工艺操作简单,投入一批原料,即可同时提取其中的光甘草定和甘草酸,为实现甘草资源高附加值的综合加工利用奠定了基础.%To study the technology of simultaneous extraction of glabridin and glycyrrhizic acid from Glycyrrhiza glabra L., the single factor experiments were done to determine the influencing factors and the orthogonal tests were done to optimize the extracting condition. The extraction conditions were optimized as follows:60％ ethanol containing 0.6％ ammonia as extractant,ratio of material to liquid 1:20 (w: v) ,extraction temperature 75 °C ,and duration was 2 h. Under these conditions,the extraction rates of Glabridin and Glycyrrhizic acid were 0.238 ±0.002％ and 5.08 ±0.03％ respectively. This technology featured simple operation and yielded the two important bioactive compounds at the same time. The research provided a basis for comprehensive development and utilization of Glycyrrhiza re sources with high valued-added.
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