白细胞介素17(IL-17)是一种由多种细胞分泌的前炎性细胞因子,具有强大的募集中性粒细胞,诱导多种趋势因子、免疫炎性因子及金属蛋白酶释放和增强自身抗体表达等促进炎症作用.研究显示IL-17在哮喘的慢性炎症与呼吸道重构中均有着重要的作用,因此提出可能实现IL-17基因的靶向治疗,为哮喘防治提供一个新的研究方向.%Interleukin 17( IL-17 )is a proinilammatory cytokine, secreted by a variety of cells, having the formidable function in promoting inflammation by inducing vaiioup rhemokinep and inflammatoiy ryto-kines, releasing metal protease and enhancing self-antibody expression. Studies showed that IL-17 has important function in the chronic inflammation and airway remolding of asthma, here is to put forward a possibility that IL-17 gene is a potential therapeutic target for treatment of asthma, providing a new research direction of prevention and treatment of asthma.
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