呼气末二氧化碳分压联合平台压监测在急性呼吸窘迫综合征机械通气中的应用进展

摘要

Acute respiratory distress syndrome(ARDS) is a common critical illness,the main clinical manifestations of which are progressive dyspnea and refractory hypoxemia.Oxygen therapy is hard to improve symptoms and hypoxemia.At present,lung protective ventilation is the standard treatment strategy for mechanical ventilation in the patients with ARDS.Permissive hypercapnia and limited plateau pressure are important for lung protective ventilation.End tidal carbon dioxide partial pressure combined plateau pressure monitoring can improve the effects of mechanical ventilation,reduce ventilator associated lung injury complications,set the reasonable modes and parameters for individual mechanical ventilation.%急性呼吸窘迫综合征(ARDS)是临床上常见的危重症,其主要的临床表现为进行性呼吸窘迫以及难治性低氧血症,常规氧疗难以缓解症状及纠正低氧血症.肺保护性通气策略是目前ARDS机械通气的标准治疗策略,允许高碳酸血症及限制平台压是肺保护性通气策略的重要手段,呼气末二氧化碳分压及平台压监测能提高ARDS的机械通气效果及减少呼吸机相关性肺损伤等并发症,合理设置符合个体化原则的机械通气模式和参数.