关节镜下自体移植与同种异体移植膝关节交叉韧带重建术对比研究

摘要

Objective:To compare the clinical efficacy difference between using autologous graft and allograft graft to reconstruct knee cruciate ligament under arthroscopy.Method:Eighty-five patients with ACL/PCL injuries which came from June 2008 to June 2012 in the hospital were divided into the autologous tendon group and allograft tendon group. Recorded and compared the operation time,hospitalization time and the incidence of adverse reactions between the two groups. One years after operation,calculated Lysholm score,Larson score and International Knee Documentation Committee(IKDC)score to appraise the joint function.Result:All the patients were followed up for 12 to 48 months. There was no severe complication, such as vascular nerve injury,infection and rupture of graft occurred in early stage after operations in the patients. Operation time of autologous group was longer than allograft group,hospitalization time was shorter than allograft group,the differences were statistically significant(P<0.001). There was no differences in Lysholm score,Larson score and IKDC score between the autologous tendon group and allograft tendon group(P>0.05).Conclusion:There is no significant differences of treatment effect in the knee cruciate ligament reconstruction between autologous tendon and allogenic tendon transplantation.%目的：探讨关节镜下自体移植与同种异体移植重建膝关节前后交叉韧带的临床疗效差异。方法：选择2008年6月-2012年6月在本院进行关节镜下膝关节交叉韧带重建术的85例患者为研究对象，将其分为自体肌腱组和同种异体肌腱组。记录并比较两组患者的手术时间、住院时间及不良反应发生情况，统计术后1年Lysholm评分、Larson评分及国际膝关节评分委员会（IKDC）评分，评价关节功能。结果：所有患者均获随访，随访12~48个月。均未发生血管神经损伤，无感染、无植入物断裂。自体组患者手术时间较异体组长，住院时间较异体组短，两组比较差异均有统计学意义（P<0.001）。自体组与异体组患者Lysholm评分、Larson评分及IKDC评分比较差异均无统计学意义（P>0.05）。结论：自体肌腱移植与同种异体肌腱移植在重建膝关节交叉韧带治疗效果中无明显差异。