致尿路感染大肠埃希菌的耐药监测及分析

摘要

Objective:Investigating the pathogens and its drug resistances of Escherichia coli causing urinary tract in-fection in order to provide a practical method for the disease control and clinical drug use .Methods:Patients with urina-ry tract infection in 2014 were investigated using retrospective method .Results:In the 814 pathogen strains isolated from urine ,260 strains were Escherichia coli ,accounting for 31 .9% of the total ,among which 124 strains carrying ES-BLs accounted for 47 .7% .The results of the drug sensitive test showed that the resistances of the Escherichia coli car-rying ESBLs were much higher than which not .Conclusion:With the increase of the amounts of Escherichia coli carry-ing ESBLs ,the resistances of the pathogen were more serious ,which made the doctors should take the dangerous fac-tors causing Escherichia coli producing ESBLs and the results of the drug sensitive test into consideration when treating the patients of U rinary tract infection .%目的：了解尿路感染患者尿液标本中大肠埃希菌的检出情况和耐药情况，指导临床合理用药。方法：采用回顾性分析，对2013年1年来医院尿路感染患者进行调查研究。结果：尿液培养分离的814株病原菌中，大肠埃希菌260株，占总数的31．9％，其中，产ESBLs大肠埃希菌124株，占47．7％。药敏结果显示，产ESBLs大肠埃希菌耐药率明显高于非产ESBLs大肠埃希菌。结论：产ESBLs大肠埃希菌的增多，加重了细菌的耐药性，临床在治疗尿路感染时应综合考虑大肠埃希菌产ESBLs的危险因素及药敏结果合理使用抗生素。