外阴阴道萎缩相关的围绝经期及绝经后女性性功能障碍(FSD)是一种较为常见的可影响许多围绝经期及绝经后妇女生活质量的临床疾病.然而研究进展却非常缓慢,使人们对该疾病的认识和治疗很有限.与男性不同的是女性会经历围绝经期及绝经期,女性从围绝经期开始,卵巢功能逐渐衰退,内分泌出现不同程度的改变,雌激素水平下降,同时,随着年龄的增加,其阴道黏膜萎缩、弹性及润滑作用均会减弱,因此,围绝经期及绝经后FSD患病率明显增加.目前认为与高龄、不良的生活方式、内分泌因素、饮酒、慢性疾病、难产、离异等多种因素密切相关.外阴阴道萎缩相关的围绝经期及绝经后FSD的治疗方法有多种,临床应根据患者的不同症状以及主要的危险因素选择最佳的治疗方法,提高患者生活质量.综述外阴阴道萎缩相关的围绝经期及绝经后FSD的相关影响因素及其治疗.%The peripheral vaginal atrophy-related sexual dysfunction (FDS) in perimenopausal and postmenopausal women is a common disease that can affect the quality of life of many perimenopausal and postmenopausal women. However, its awareness and treatment are very limited. Those perimenopausal women experience the gradually declined ovarian function, with endocrine variation, and decreased estrogen. At the same time, their vaginal mucosa atrophied, elasticity and lubrication will be weakened. Therefore, the prevalence of sexual dysfunction was increased in perimenopausal and postmenopausal women. It was reported that FSD was closely related to age, poor lifestyle, endocrine factors, alcohol consumption, chronic diseases, dystocia, divorce and other factors. The treatment of the vulvovaginal atrophy-related FSD in those perimenopausal and postmenopausal women should be based on their symptoms and main risk factors, in order to improve the quality of life. This paper reviewed the risk factors and treatment of vulvovaginal atrophy-related FSD in those perimenopausal and postmenopausal women.
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