血脂异常与冠心病相关性的临床观察

摘要

目的：探讨血脂异常与冠心病的相关性。方法选择我院心内科2010年1月-2012年12月行冠脉造影术的532例住院患者，其中：男293例，女239例。分为冠心病组426例、非冠心病组106例。分析其临床资料，用统一方法、统一试剂及标准方法检测血脂水平，分析总胆固醇（ TC）、甘油三酯（ TG）、低密度脂蛋白（ LDL-C）、高密度脂蛋白（HDL-C）等血脂蛋白水平的指标与冠心病的相关性。结果冠心病患者TC升高者128例（30．1％）， TG升高者180例（42．3％），LDL-C 升高150例（35．2％），均显著高于非冠心病组 TC 升高16例（15．2％），TG 升高28例（26.4％），LDL-C升高21例（19．8％）。冠心病组HDL升高22例（5．2％）明显低于非冠心病组15例（14．2％）。结论高TC 、TG、LDL-C与低HDL-C是冠心病的重要危险因素，因此积极预防和控制血脂异常是冠心病防治的重要措施。%Objective To study the correlation of dyslipidemia and coronary heart disease (CHD).Methods 532 cases of hospitalized patients of our department (male 293,female 239) between January 2010 and December 2010,who had underg-one coronary angiography ,were selected and divided into a CHD group ( n=426 ) and a non-CHD group ( n=106 ) .Their clinical data were analyzed ,using unified method ,reagent and standard to detect the blood lipid level ,and to analyze the corre-lation between lipid protein level indicators ( TC,TG,LDL-C,HDL-C) and coronary heart disease .Results Of the patients in the CHD group,there were 128 cases (30.1%) of TC rise,180 cases (42.3%) of TG rise and 150 cases (35.2%) of rise in LDL-C.The indicators were significantly higher than those in the non-CHD group (16 cases of TC rise,15.2%;28 cases of TG rise,26.4%;21 cases of LDL-C rise,19.8%).22 cases(5.2%) in the CHD group had HDL rise,obviously lower than 15 ca-ses (14.2%) in the non-CHD group.Conclusion High TC,TG,LDL-C,and low HDL-C are significant risk factors for coro-nary heart disease ,so positive prevention and control of dyslipidemia are important measures of prevention and treatment of cor -onary heart disease .