产后使用卡前列素氨丁三醇时机对产后出血影响的临床研究

摘要

目的 探讨产后阴道出血量达到300 ml和500 ml时使用卡前列素氨丁三醇对产后出血影响.方法 选取2015年10月至2017年10月在本院住院经阴道分娩后出血量达到300 ml以上产妇180例为研究对象,用随机分组表法分为干预组(出血量达到300 ml时给予卡前列腺素氨丁三醇治疗,90例)和对比组(出血量达到500 ml时给予卡前列腺素氨丁三醇治疗,90例),比较两组产妇产后2h、24 h出血量,产后出血发生率及输血情况.结果 干预组产妇产后2h、产后24 h出血量均少于对比组(均P＜0.05).干预组产妇产后出血、输血率均低于对比组[8.89％比21.11％,4.44％比16.67％,均P＜0.05].结论 产后出血量较多的产妇,在早期给予卡前列素氨丁三醇治疗,能减少产妇总出血量,降低产后出血、输血发生率.%Objective To investigate the effect of using carprostol tromethamine when postpartum vaginal bleeding reaches 300 ml and 500 ml on postpartum hemorrhage.Methods select 180 women with a bleeding volume more than 300 ml during transvaginal delivery after hospitalization at our hospital from October,2015 to October,2017 were selected as study objects,and were randomly divided them into an intervention group (n=90,treated with prostaglandin tromethamine when the bleeding volume reached 300 ml) and a control group (n=90,tereated with prostaglandin tromethamine when the bleeding volume reached 500 ml).The bleeding volumes 2 and 24 h after delivery and the incidences of postpartum hemorrhage and blood transfusion were compared between the two groups.Results The bleeding volumes 2 and 24 h after delivery were higher in the intervention group than in the control group (both P ＜ 0.05).The incidences of postpartum hemorrhage and blood transfusion were lower in the intervention group than in the control group (8.89％ vs.21.11％ and 4.44％ vs.16.67％,both P ＜ 0.05).Conclusions Early treatment with carprostol tromethamine for patients with large postpartum hemorrhage can reduce the total bleeding volume and reduce the incidences of postpartum hemorrhage and blood transfusion.