目的 探讨延续性护理干预对乳腺癌口服分子靶向药物治疗患者用药依从性及自护能力的影响.方法 2016年6月至2017年1月选取120例口服分子靶向药物治疗的乳腺癌患者,根据随机数字表将患者分为观察组(n=60)及对照组(n=60),对照组用药期间采用常规性护理,观察组用药期间对其实施延续性护理干预,干预时间为6个月,比较两组患者疾病知识、用药依从性及自护能力情况.结果 观察组患者用药依从性、疾病知识知晓率、近期用药有效率高于对照组,而不良反应率低于对照组(P<0.05).观察组干预后3个月、6个月自我效能总评分、健康知识、自我护理技能、自我概念、自护责任感评分显著高于对照组(P<0.05).结论 延续性护理干预能有效提高乳腺癌口服分子靶向药物治疗患者依从性及自我护理能力,降低患者用药不良反应,提高患者用药效果.%Objective To explore the effect of continuing nursing intervention on medication compliance and self-care ability in breast cancer patients undergoing oral molecular targeted drug therapy. Methods 120 cases of patients with breast cancer treated with oral molecular targeted drugs were divided into observation group (n=60) and control group (n=60) according to the random number table from June 2016 to January 2017. The control group was treated with routine care, while the observation group was treated with continuing nursing intervention. The duration of intervention was 6 months, and the knowledge, medication compliance, and self-care ability were compared between the two groups. Results The rate of medication compliance, the awareness rate of disease related knowledge, the effective rate of short-term medication in the observation group were significantly higher than those in the control group, and the adverse reaction rate was lower than that in the control group (P<0.05). 3, 6 months after intervention, the scores of self - efficacy, health knowledge, self - care skills, self - concept, and self - care responsibility of the observation group were higher than those of the control group (P<0.05). Conclusion Continuing nursing intervention can effectively improve the medication compliance and self - care ability of breast cancer patients undergoing oralmolecular targeted drug therapy, reduce the adverse reactions, and improve the effect of drug use.
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