AIM: To compare the change of visual quality of femtosecond-laser in situ keratomileusis ( FS-LASIK) and laser in situ keratomileusis ( LASIK) for myopia. METHODS: A retrospective case series. A total of 89 cases 178 eyes were chosen from Jan. 2014 to Dec. 2015. There were 46 cases (92 eyes) in FS-LASIK and 43 cases 86 eyes in LASIK. The visual acuity, refraction state, subjective visual quality score, high order aberration were measured at 6mo after surgery. RESULTS: All patients underwent operation smoothly, and no complication was observed during and after surgery; there was no statistically significant difference between two groups at visual acuity (P>0. 05). Postoperative diopter compared with preoperative expectations diopter difference is statistically significant between two groups (P0.05),两组患者术后屈光度与术前预期屈光度比较,差异具有统计学意义(P<0.05)。两组患者术后6mo主观视觉调查质量评分比较,差异有统计学意义(P<0.05)。术后6 mo飞秒激光组和机械板层刀组角膜像差均方根值、球差及彗差较术前增加,差异具有统计学意义(P<0.05),但飞秒激光组增加的幅度比机械板层刀组低,差异有统计学意义(P<0.05)。 结论：飞秒激光制作角膜瓣更精确可靠,离散度更小,可以制作更薄的角膜瓣,飞秒激光制瓣的LASIK较传统机械板层刀LASIK术后可以获得更好的视觉质量。
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