首页> 中文期刊> 《国际眼科杂志》 >光学相干断层扫描在高度近视黄斑病变中的应用研究

光学相干断层扫描在高度近视黄斑病变中的应用研究

         

摘要

AIM: To investigate the value of optical coherence tomography (OCT) in maculopathy of high myopia. METHODS: Totally 50 patients (50 affected eyes) with high myopia who were admitted to our hospital during the period from June 2016 to May 2017 were prospectively enrolled in the observation group, and 50 normal healthy people(50 eyes) were selected as the control group at the same time. All subjects completed the conventional ophthalmic examination and OCT after admission. The visual acuity, intraocular pressure, diopter, eye axis, macular thickness and morphological changes were recorded, and detection of maculopathy of high myopia by different examination methods was statistically analyzed. RESULTS: Conventional ophthalmic examination showed that the macular region was normal in 37 eyes and abnormal in 13 eyes (26%) while OCT showed that it was normal in 12 eyes and abnormal in 38 eyes (76%) in the observation group. The rate of maculopathy detected by OCT was higher than that by conventional ophthalmologic examination, with a significant difference (P 0. 05). The intraocular pressure, diopter and axial length of patients with high myopia and maculopathy were higher/longer than those of the control group, the BVCA was worse than that of the control group, the thickness of retinal macular region, thickness of nerves above and below the optic disc, thickness of optic nerves on the bitamporal and nasal sides of the optic disc were lower than those of the control group, with significant differences (P0.05).(2)高度近视黄斑病变患者眼压、屈光度、眼轴长度高于对照组,BVCA较对照组差,视网膜黄斑区厚度、视盘上方神经厚度、视盘下方神经厚度、视盘颞侧视神经厚度、视盘鼻侧视神经厚度均低于对照组,差异有统计学意义(P<0.05).结论:OCT可定量测定高度近视患者视网膜周围神经纤维层厚度,清晰显示黄斑区病变特点,可为高度近视黄斑病变诊断提供可靠的定量数据.

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