糖尿病肾病患者血清载脂蛋白B和超敏C反应蛋白与血清半胱氨酸蛋白酶抑素C的关系

摘要

Objective: To study the relationship of Apo-B, hs-CRP and Cystatin C. Method : 118 cases with diabetic nephropathy, 106 cases with type 2 diabetic without complications, The control group were 82 healthy individuals. Parameters Apo-B, hs-CRP, Cys-C,compared the relation of Apo-B hs-CRP and Cys-C. Results: The levels of Apo-B and hs-CRP in diabetic nephropathy group is higher than normal control group and type 2 diabetic without complications group ( P < 0. 05). Conclusion:The Cys - C in diabetic nephropathy have a higheiaccuracy , Apo-B and hs-CRP may important roles in the pathogenesis of diabetic nephropathy.%目的:探讨载脂蛋白B(Apo-B)和超敏C反应蛋白(hs-CRP)与血清半胱氨酸蛋白酶抑素C(Cys-C)的关系.方法:对118例糖尿病肾病患者、106例2型糖尿病患者和82例正常对照者,分别测定血清Apo-B、hs-CRP、Cys-C,比较各组血清Apo-B、hs-CRP的水平及与Cys-C的相关性.结果:糖尿病肾病患者血清Apo-B、hs-CRP Cys-C明显高于对照组及2型糖尿病患者.结论:Cys-C在糖尿病肾病早期有较高的准确性,更进一步表明Apo-B、hs-CRP与糖尿病肾病的发生、发展相关.