我院门急诊抗菌药物处方评价及合理性分析

摘要

目的 对我院门急诊的抗菌药物处方进行评价并进行合理性分析,推进我院的药物使用规范.方法 本次的参考标准为《处方管理办法》《新编药物学》(17版)《抗菌药物临床应用指导原则》《抗菌药物临床应用管理办法》《医院处方点评管理规范(试行)》,随机抽取我院2017年7月至9月2400张门急诊抗菌药物处方进行统计分析,评价其用药合理性.结果 抗菌药物的临床使用以单一用药为主,占94.4％,二联用药占5.6％,仅发现1例三联用药;β-内酰胺类抗菌药物使用率最高,其次为克林霉素及大环内酯类.2400张抗菌药物处方中,不合理用药处方90张,不合理用药率为3.75％,主要为无指征应用抗菌药物、联合用药不适宜、遴选的药品不适宜等.结论 我院门、急诊抗菌药物的使用基本合理,但仍有不合理用药情况,应引起临床重视,以提高抗菌药物合理使用水平.%Objective Prescription evaluation and rationality analysis of antibiotics in our outpatient and emergency department.Methods The reference standard is "prescription management method" "new Pharmacology" (17 Edition), "guidelines for clinical application of antibacterial drugs", "management method of clinical application of antibacterial drugs", with "hospital prescription review management standard" as the standard, 2400 doors and emergency cases from July 2017 to September 2017 in our hospital were randomly selected.The prescriptions of antimicrobial agents were statistically analyzed to evaluate the rationality of their use.Results The clinical use of antibiotics was mainly a single drug, accounting for 94.4％ (2266/2400), two combined use of 5.6％ (134/2400), only one case of triple drugs was found;the use of beta lactam antibiotics was the highest, followed by clindamycin and macrolide.Of the 2400 antibiotic prescriptions, 90 prescriptions for irrational drug use and 3.75％ of the irrational drug use rate were the unsuitable application of antibiotics, unsuitable combination of drugs and inappropriate selection of drugs.Conclusion The use of antibiotics in our hospital and emergency department is basically reasonable, but there are still irrational use of drugs, which should be paid attention to in order to improve the rational use of antibiotics.