小儿嗜肺军团菌肺炎合并肺炎支原体感染的临床特征分析

摘要

目的：探讨小儿嗜肺军团菌肺炎合并肺炎支原体感染的临床特征。方法回顾性分析2008年8月至2013年8月我院收治的50例嗜肺军团菌肺炎患儿的临床资料，其中单纯嗜肺军团菌感染患儿34例(对照组)，合并肺炎支原体感染患儿16例(观察组)，对两组患儿的临床特征进行对比分析。结果混合感染多见于城镇的学龄前儿童。在临床表现方面，观察组热峰高、热程长、肺部阳性体征、心率加快、颈部淋巴结肿大及肝脏增大的发生率明显高于对照组，住院时间明显长于对照组，差异具有统计学意义(P<0.05)；在辅助检查方面，观察组胸片大片斑片影和胸腔积液，WBC增高、CRP增高，CK-MB增高、心电图阳性表现(包括心动过速/ST-T改变)、肝功能异常的发生率明显高于对照组，差异具有统计学意义(P<0.05)。结论小儿嗜肺军团菌肺炎合并肺炎支原体感染肺部症状体征重、易合并肺外器官损害，应积极的开展多中心、大样本的研究以获得更加可靠的资料，为临床防治提供帮助。%Objective To investigate the clinical features of children's Legionella pneumophila pneumonia combine mycoplasma pneumoniae infection. Methods Retrospectively analysis the clinical data of 50 cases of chil-dren with Legionella pneumophila pneumonia in our hospital from August 2008 to August 2013, 34 cases of children with simple Legionella pneumophila infection (control group), 16 cases of children combined mycoplasma pneumoniae infection (observation group), Analyzed and compared the clinical features of two groups . Results The mixed infec-tion seen more among urban preschool children. In terms of clinical manifestation, The thermal spike of observation group higher, thermal time longer than control group, the incidence of positive signs of lung, heart rate, cervical lymph node enlargement, and an increase of liver of observation group were significantly higher than the control group, hos-pital stay longer than the control group, have statistically significant difference (P<0.05);In terms of auxiliary exami-nation, the incidence of the chest radiography large patch shadow and pleural effusion, WBC increased, CRP in-creased, CK-MB increased, electrocardiogram (ECG) positive performance including tachycardia and ST-T change, abnormal of liver function of the observation group were significantly higher than the control group, difference has sta-tistical significance (P<0.05). Conclusion The lung signs and symptoms of the children's Legionella pneumophila pneumonia combine mycoplasma pneumoniae infection was serious, easy to merge extrapulmonary organ damage, should actively carry out multicenter, large sample research in order to obtain more reliable data, provide help for clini-cal prevention and cure.