Objective To explore the relationship between nonalcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) and to evaluate the value of NAFLD in predicting MS in professional women .Methods 8 769 professional women with health physical examination during 2 010 were performed the current status survey ,physical examination ,biochemical detection and B-type ultrasound for analyzing the correlation between fally liver with MS and its components .Results Among 8 769 professional women,the detection rate of MS was 9.75% ,NAFLD was 7.85% .With increasing of age ,the detection rate of NAFLD and MS was increased .Abdominal obesity and NAFLD had most close relation in the five components of MS ,and RR reached 16 .41 .Compared with abdominal obesity and overweight ,NAFLD had the highest percentage in the specificity ,accuracy ,positive predictive value .Low HDL-C ,high TG detection rate was not increased with increasing BMI among 688 cases of fatty liver after BMI stratification .Three or more MS components aggregation rate was 30.89% in the normal-weight patients with fatty liver ,63.00% in the o-verweight group and 71.88% in the obese group .Conclusion MS is closed related with NAFLD ;Fatly liver can better determine MS ;NAFLD can be used as a component of MS .%目的 探讨在职女性非酒精性脂肪肝(NAFLD)与代谢综合征(MS)的关系,评估脂肪肝判别MS的价值.方法 对2010年全年参加健康体检的8 769例在职女性进行现况调查、体检、生化检验、肝胆脾实时B超检查,对脂肪肝与MS及其组分的相关性进行分析.结果 8 769例职业女性MS检出率为9.75%(855/8 769),NAFLD检出率为7.85%(688/8 769).随着年龄的增加,MS、NAFLD检出率均增高,MS 5个组分中,腹型肥胖与NAFLD的关系最密切,相对危险度(RR)达到了16.41.腹型肥胖、超重、NAFLD判别MS的比较后发现,NAFLD判断MS的敏感性虽然低于腹型肥胖,但高于超重.NAFLD判定的特异度,正确指数,阳性预测值最高.688例脂肪肝患者BMI分层后MS各组分异常的阳性率比较发现,低高密度脂蛋白胆固醇(HDL-C),高三酰甘油(TG)检出率并不随BMI增加而增高.体质量正常的脂肪肝患者,3项以上MS组分聚集率为30.89%,超重组为63.00%,肥胖组为71.88%.结论 脂肪肝与MS密切相关,脂肪肝可以较好的判定MS,NAFLD可作为MS的一个组成成分.
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