部分性发作癫痫患者的认知功能损害与情绪障碍的分析

摘要

目的：分析部分性发作癫痫患者的认知功能损害与情绪障碍的特点。方法：对78例部分性发作癫痫患者和60例性别、年龄和教育程度匹配的正常健康对照者组，采用韦氏数字广度测验（ DST）、言语流畅性测验（ VFT）量表进行认知功能评估，采用抑郁自评量表（ SDS）和焦虑自评量表（ SAS）进行情绪状态评估，并进行分析。结果：癫痫患者组的DST评分、VFT评分均较正常组低，差异具有统计学意义（p＝0．000，p＝0．000）；癫痫患者组SDS评分和SAS评分均较正常组高，具有统计学差异（p＝0．001，p＝0．001）；癫痫患者中认知功能及情绪障碍相关分析显示，DST评分与VFT评分，SDS评分与SAS评分均呈显著性正相关性（p＜0．01）。结论：部分性发作癫痫患者存在记忆、语言方面的认知功能损害，并且存在明显的抑郁和焦虑情绪。神经精神量表是客观的评价癫痫患者神经心理状况的方便、有效手段。%Objective:To analysis the cognitive function and emotional state of the patients with partial epilepsy ,Methods:78 patients with partial epilepsy and 60 healthy controls with equivalent gender , age and education level were assessed by digital span test ( DST) and verbal fluency test ( VFT) of Wechsler adult intelligence scale ( WAIS) , self-rating depression scale ( SDS) , self-rating anxiety scale (SAS).Results:Digital span test was significantly lower in patients compared with controls (p=0.000, p=0.000).In verbal fluency test, the patients produce significantly less correct words than the controls (p=0.000).The scores of SDS and SAS are significantly high-er in patients compared with controls(p=0.001,p=0.001);The significant positive correlation were observed between scores of DST and VFT, the scores of SDS and SAS(P<0.01).Conclusion:The cognitive function of the partial epilepsy patients was impaired , with de-pression and anxiety as common symptoms in the patients .The neuropsychic scale might be the convenient and effective method to estimate the neuropsychic state of epilepsy patients .