具有平面手性和中心手性的二茂铁基亚砜膦配体的合成及其催化活性

摘要

通过二茂铁侧链上具有手性中心的杂原子的邻位导向作用合成了具有平面手性和中心手性的二茂铁亚砜膦配体(3),其结构经1H NMR,13C NMR,IR,MS和元素分析表征.将络合物Pd-3用于催化1,3-二苯基-2-丙烯基乙酸酯与丙二酸二甲酯/氢化钠的模板反应,收率92％,20％ee.%A ferrocenyl phosphinosulfoxide ligand(3) with planar and central chirality was synthesized by ortho-directed metalation of side chain of ferrocene at the α-position. The structure was confirmed by 1H NMR, 13C NMR, IR, MS and elemental analysis. Catalytic activity of complex Pd-3 was investigated by the standard reaction of 1,3-diphenyl-2-propenyl acetate with dimethylmalonate/ NaH. The yield of product was 92% with 20% ee.