《中国胃肠胰神经内分泌肿瘤专家共识》胰腺神经内分泌肿瘤外科治疗部分解读

摘要

胰腺神经内分泌肿瘤（pNENs）发病率近年逐渐增加，规范pNENs治疗非常重要。局部可切除或经新辅助治疗后降期的肿瘤，应积极手术切除；对局部晚期或者转移性肿瘤，减瘤术未能延长病人存活期，但对功能性pNENs，减瘤术可在一定程度上改善病人的生活质量。针对肝转移灶的积极治疗措施，包括手术、射频或介入，有望使病人获得长期生存，针对pNENs肝转移的肝移植应谨慎开展。%The incidence of pancreatic neuroendocrine neoplasm is steadily increasing in recent years. It is important to standardize the treatment of pancreatic neuroendocrine neoplasm. Localized or down-staged tumor after new adjuvant therapy should be resected. Debulking could not prolong the survival of local advanced or metastatic tumor patients, but could improve the quality of life in patients of functional tumor. Aggressive treatment of liver metastasis such as combination of surgery, RFA or TACE may achieve long term survival in metastatic patients. Liver transplantation should be accomplished with caution.