正常胰腺与腹主动脉强化峰值和峰值时间的相关性研究

摘要

目的 探讨正常胰腺与腹主动脉强化峰值和峰值时间的相关性.资料与方法 前瞻性研究行上、中腹部增强CT检查的患者62例,先平扫再选择最佳胰腺灌注层面行CT扫描.所有数据传输至Vitrea 2.0后处理工作站,采用Toshiba软件绘制时间-密度曲线(TDC)并分别计算正常胰腺和腹主动脉强化峰值和峰值时间.结果 与腹主动脉比较,正常胰腺强化峰值较低,差异有统计学意义[(111.94±14.42) HU比(351.83±74.93) HU,P＜0.05],两者的强化差值为(246.10±65.86) HU;与腹主动脉比较,正常胰腺的峰值时间较长,差异有统计学意义[(37.56±6.90)s比(30.82±6.73)s,P＜0.05],两者的时间差值为(6.54±2.97)s.正常胰腺与腹主动脉强化峰值和峰值时间均呈正相关(r=0.438、0.379,P＜0.05).结论 正常胰腺的最佳强化值与腹主动脉不同步,胰腺峰值时间比腹主动脉延迟了6～8 s,这为胰腺扫描时间窗的确定提供了依据.%Purpose To explore the correlation between normal pancreas and abdominal aorta in the peak enhancement (PE) and the shift time at the peak by applying the multislices spiral CT perfusion imaging.Materials and Methods Prospectively analyzed 62 patients who received enhancement CT examination for the superior or the middle abdomen,underwent optimum level CT perfusion imaging after plain scanning.These data were processed on a Vitreal 2.0 worker-station by using Toshiba body software package.The time-density curves (TDC) of the normal pancreas and the abdominal aorta were drawn,the PE and the shift time of PE were recorded and their correlation was analyzed.Results Compared with abdominal aorta,the mean value of PE of the normal pancreas was lower,and the difference was statistically significant [(111.94± 14.42)HU vs (351.83 ± 74.93)HU,P＜0.05],the mean difference was (246.10± 65.86)HU.Compared with abdominal aorta,the mean shift times of PE of the normal pancreas was latter,and the difference was statistically significant [(37.56±6.90) s vs (30.82±6.73) s,P＜0.05],the mean difference was (6.54±2.97)s.The PE and shift time of PE of the normal pancreas were positively and linearly correlated with that of abdominal aorta (r=0.438,r=0.379).Conclusion The PE of the normal pancreas is not synchronous with that of the abdominal aorta.The shift time of the former is usually 6～8 seconds slower than that of the latter.This provides a basis to find the PE of the normal pancreas in enhanced scan.