Objective To understand the association between the cognitive degree of disease-related knowledge and the rates of antiviral treatment in CHB patients, a survey on the disease-related knowledge and current antiviral treatment situation was carried out. Methods According to the CHB disease-related knowledge, a questionnaire was designed. From October 2011 to October 2013, questionnaire survey was conducted among a CHB patients cohort in Beijing Ditan Hospital, Capital Medical University. Results Total of 930 survey questionnaires were distributed and 881 valid questionnaires returned. The cognitive degree was divided into low, middle and high levels. There were 881 patients who with low, middle and high prevention knowledge were 17.71%, 30.76%, 51.53%, respectively;who with low, middle and high basic knowledge were 22.02%, 38.71%, 39.27%, respectively;who with low, middle and high treatment knowledge were 57.43%, 15.89%, 26.67%, respectively. Among them, 548 patients were undergoing antiviral therapy, accounting for 62.20%of all patients. The proportion of CHB patients with low general disease-related knowledge who was undergoing antiviral treatment was signiifcantly lower than the other groups. conclusions Currently, CHB patients had low disease-related knowledge, powerful propaganda and education should be strengthened by medical personnel.%目的：调查CHB患者疾病相关知识的认知情况及其抗病毒治疗现状，分析患者对疾病相关知识的认知度与接受抗病毒治疗的相关性。方法依据CHB疾病相关知识设计调查问卷，对2011年10月至2013年10月首都医科大学附属北京地坛医院收治的CHB队列中部分患者进行问卷调查。结果本次调查共发放问卷930份，回收有效问卷881份（有效率94.73%）。将患者对疾病相关知识的认知程度分为较差、一般、较好3个层次。881例患者中，对预防知识的认知较差、一般、较好比例分别为17.71%、30.76%、51.53%，对基础知识的认知比例分别为22.02%、38.71%、39.27%，对治疗知识的认知比例分别为57.43%、15.89%、26.67%。正在进行抗病毒治疗的患者548例，占患者总数的62.20%，疾病相关综合知识认知较差组CHB患者抗病毒比例明显低于其他组CHB患者。结论目前患者对CHB疾病相关知识认知较差，医务人员应加强对患者的宣教。
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