双三唑席夫碱哒嗪酮衍生物的合成及其生物活性

摘要

设计合成了9种未见文献报道的双三唑席夫碱哒嗪酮化合物.用1H NMR、13C NMR、IR及元素分析表征结构.生物活性初步结果表明,在500 mg/L浓度下部分化合物对黄瓜花叶病毒(CMV)、小麦赤霉病菌(G.zeae)、辣椒枯萎病菌(F.oxysporum)和苹果腐烂病菌(C.mandshurica)有一定抑制作用.%Nine novel pyridazinone derivatives containing 1,2,4-triazolo and Schiff base were synthesized. Their structures were characterized by !H NMR, 13C NMR, IR and elemental analyses. The preliminary bioassay showed that, under 500 mg/L concentrations, some of them exhibited certain anti-cucumber mosaic virus (CMV) , G. Zeae, F. Oxysporum and C. Mandshurica activities and fungicidal activities.