银杏叶提取物治疗慢性阻塞性肺疾病作用机制的研究进展

摘要

慢性阻塞性肺疾病(COPD)是一种累及气道、肺实质和肺血管的慢性炎症,其特征为不完全可逆性气流受限呈进行性发展.随着当今医疗技术的发展,人们对于COPD有了更深入的了解,西医诊疗技术也有了较大进步,但其发病率及病死率仍居高不下.因此如何在原有西医治疗的基础上找到新的治疗方法成为当前研究的热点之一.近年来有关银杏叶提取物(GBE)治疗COPD的研究取得了一定成就,本文就其作用机制进行概述,为临床GBE治疗COPD提供一定的理论参考.%Chronic obstructive pulmonary disease(COPD) is a kind of chronic inflammation involving the airway,lung parenchyma and vessels,which is characterized by progressive development of incompletely reversible airflow limitation.With the development of medical technology,interventions for COPD have made great progress,but the incidence and mortality of COPD remain high.Therefore,finding the new treatment regimen on the basis of western medicine therapy becomes a focus of current research.As treating COPD with Ginkgo biloba extract(GBE) has obtained some achievements in recent years,we reviewed the mechanism of GBE in treating the disease,with a view to providing a theoretical reference for clinical treatment.